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KMID : 0367320140250010014
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Journal of the Korean Academy of Child and Adolescent Psychiatry
2014 Volume.25 No. 1 p.14 ~ p.19
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Prescribing Patterns for Treatment of Pediatric Bipolar Disorder in a Korean Inpatient Sample
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Kwon O-Hyang
Park Su-Bin
Lee Su-Min
Kim Jae-Won
Shin Min-Sup
Yoo Hee-Jeong
Cho Soo-Churl
Kim Bung-Nyun
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Abstract
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Objectives : This study was conducted in order to describe prescribing practices in treatment of pediatric bipolar disorder in a Korean inpatient sample.
Methods : We performed a retrospective chart review of 66 youths who had been hospitalized and diagnosed with bipolar disorder according to the Diagnostic and Statistical Manual of Mental Disorders, fourth edition criteria. Demographics, clinical characteristics, medications used, doses, and related adverse events were examined.
Results : Mood stabilizers and/or atypical antipsychotic medications were the primary treatment. Risperidone, valproate, and lithium were the most commonly used. Thirty seven patients (58.1%) were treated with combination therapy of an atypical antipsychotic and mood stabilizer for improvement of manic/mixed symptoms.
Conclusion : Combination pharmacotherapy was necessary for most patients in this admission sample group. Conduct of further studies will be needed for evaluation of treatment response according to the clinical characteristics, and the safety and efficacy of treatment for child and adolescent bipolar disorder.
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KEYWORD
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Bipolar Disorder, Pharmacotherapy, Children and Adolescents
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